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Carolina Perez-Pastene Selected Research

aminochrome 1 (aminochrome)

10/2009Molecular and neurochemical mechanisms in PD pathogenesis.
9/2007Aminochrome as a preclinical experimental model to study degeneration of dopaminergic neurons in Parkinson's disease.
5/2007Association of GST M1 null polymorphism with Parkinson's disease in a Chilean population with a strong Amerindian genetic component.
7/2004On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation.
11/2002Oxidation of dopamine to aminochrome as a mechanism for neurodegeneration of dopaminergic systems in Parkinson's disease. Possible neuroprotective role of DT-diaphorase.

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Carolina Perez-Pastene Research Topics

Disease

6Parkinson Disease (Parkinson's Disease)
10/2009 - 11/2002
1Parkinsonian Disorders (Parkinsonism)
05/2009
1Hepatolenticular Degeneration (Wilson's Disease)
05/2009
1Necrosis
07/2004
1Edema (Dropsy)
07/2004

Drug/Important Bio-Agent (IBA)

5aminochrome 1 (aminochrome)IBA
10/2009 - 11/2002
3Dopamine (Intropin)FDA LinkGeneric
05/2007 - 11/2002
1neuromelaninIBA
10/2009
1CopperIBA
05/2009
1Levodopa (L Dopa)FDA LinkGeneric
09/2007
1Leucine (L-Leucine)FDA Link
07/2007
1Phosphotransferases (Kinase)IBA
07/2007
1Proteins (Proteins, Gene)FDA Link
07/2007
1Glutathione Transferase (Glutathione S-Transferase)IBA
05/2007
1EnzymesIBA
07/2004
1Dicumarol (Dicoumarol)FDA Link
07/2004
1NeurotoxinsIBA
07/2004
1Fluorescent Dyes (Fluorescent Probes)IBA
07/2004
1NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA
07/2004
1Hydroxyl RadicalIBA
07/2004
1Free RadicalsIBA
11/2002

Therapy/Procedure

1Therapeutics
09/2007